DNA Replication
A process of DNA making a copy of itself
Happens in S phase of Interphase
Steps
DNA Unwinds
DNA unzips
double and triple hydrogen bonds between nucleotides are broken
forms replication forks
New DNA complementary nucleotides are added to the exposed bases
New strands reform helices
Enzymes Used
Helicases
unwind and unzip DNA
DNA polymerase
bonds complementary nucleotides to exposed bases
Ligase
bonds the nucleotides together to form a strand
Mutations
changes in the DNA sequence
causes a change in the protein produced
Repair Enzymes
check DNA to find mismatched pairs
A-T
C-G
Nondisjunction is not a mutation
happens in meiosis
Sun Cancer
causes nitrogen bases on one side of identical nucleotides next to each together to join
causes a "kink" in the perfect double helix shape of DNA
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